ANKRD18B

Across TCGA cell cohorts, ANKRD18B mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD18B-associated genes across cancer lineages are TBL1Y, GUCA1C, and KCNK16. Each is linked with ANKRD18B in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD18B-to-partner and partner-to-ANKRD18B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBL1Y grouped by ANKRD18B-low versus ANKRD18B-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD18B→partner) and Y-score (partner→ANKRD18B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TBL1Y →	+0.053	+4.643	<.001	.008	3	1
LUNG_SCLC	GUCA1C →	+0.416	+4.817	<.001	.001	3	1
BREAST	KCNK16 →	+0.024	+4.672	.003	.002	3	1
SKIN	OXT →	+0.063	+4.977	<.001	.007	3	1
SKIN	AVPR1B →	+0.006	+5.415	.007	.004	3	1
LARGE_INTESTINE	SNX3 →	+0.441	+3.237	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

TBL1Y by ANKRD18B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →