ANKRD16

Across TCGA patient cohorts, ANKRD16 protein abundance is significantly associated with the RNA expression of many other genes, with 6,016 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANKRD16-associated genes across cancer lineages are PRDM8, ZDHHC4P1, and MTND4P15. Each is linked with ANKRD16 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD16-to-partner and partner-to-ANKRD16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD16 versus PRDM8 in HNSC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD16→partner) and Y-score (partner→ANKRD16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRDM8 →	-0.533	-0.265	.004	.001	3	4
HNSC	ZDHHC4P1 →	-0.844	-0.261	.003	.001	3	4
UCEC	MTND4P15 →	-0.608	-0.238	<.001	.001	3	3
UCEC	RAP1AP →	-0.999	-0.208	<.001	.003	3	3
HNSC	APOL4 →	-0.703	-0.258	.007	.001	3	3
LSCC	IFI44 →	-0.861	-0.254	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,016 associations by consensus.

ANKRD16 vs PRDM8 — HNSC

Explore this scatter interactively →