Q-omics provides the consensus-scored MTND4P15 profile across patient tissues and cancer cell-line models. MTND4P15 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, MTND4P15 is differentially expressed in 5, with the highest sampling consensus in HNSC. Additionally, MTND4P15 RNA expression shows 10,689 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight UVM, HNSC, and THYM as cancer lineages where MTND4P15 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND4P15 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND4P15 survival associations across molecular data types. MTND4P15 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND4P15 RNA expression–survival associations across cancer types. High MTND4P15 expression shows unfavorable associations in UVM, CESC, COAD and MESO, but favorable associations in ACC and KIRP. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify UVM as the clearest survival context for MTND4P15 RNA expression.
This table summarizes MTND4P15 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for MTND4P15. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND4P15 shows lower tumor expression in THCA and KIRP and higher tumor expression in HNSC, LUSC and LIHC. The HNSC box plot shows higher MTND4P15 RNA expression in tumor versus normal tissue (log2 FC = +0.088, t-test p = .003).
This table shows molecular features associated with MTND4P15 in patient tissues and cancer cell lines. In patient samples, MTND4P15 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
