ANKRD13D

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD13D mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD13D-associated genes across cancer lineages are JNK2, Lck, and PDK1_pS241. Each is linked with ANKRD13D in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD13D-to-partner and partner-to-ANKRD13D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by ANKRD13D-low versus ANKRD13D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD13D→partner) and Y-score (partner→ANKRD13D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECJNK2 →+0.299+2.817.002.03631
UCECLck →+0.261+3.459.009.00531
UCECPDK1_pS241 →+0.176+3.000.040.03631
UCECAMPK_pT172 →+0.429+2.335.037.02031
UCECShc_pY317 →-0.189-3.000.013.03631
UCECCaspase-7-cleavedD198 →+1.035+3.189<.001.01031
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

JNK2 by ANKRD13D expression — UCEC

Box plot of JNK2 in ANKRD13D-low vs ANKRD13D-high samples in UCEC.

Explore this box plot interactively →

Exploration