Across TCGA pan-cancer cohorts, ANKRD13C mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ANKRD13C data layer compared with 24 for mass-spec protein and 6 for mutation status.
The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ANKRD13C mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ANKRD13C expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.
LSCC and LUAD are the cancer types where ANKRD13C mass-spec protein most reproducibly stratifies survival.