ANKRD13C

Across TCGA pan-cancer cohorts, ANKRD13C RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ANKRD13C’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ANKRD13C RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ANKRD13C is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, KICH, and THCA are the cancer types where ANKRD13C tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANKRD13C RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.378	<.001	9	view →
KICH	Female	All	−1.256	<.001	8	view →
THCA	All	II,III,IV	−0.461	<.001	8	view →
LIHC	Male	All	+0.582	<.001	7	view →
STAD	All	II,III,IV	+0.458	.012	4	view →
CHOL	Female	All	+2.146	<.001	3	view →
READ	All	All	−0.518	.007	3	view →
KIRC	Female	III,IV	+0.386	.011	3	view →
COAD	All	All	−0.360	.011	3	view →
BRCA	All	II,III,IV	+0.145	.026	2	view →
KIRP	Male	All	−0.264	.034	1	view →
LUAD	All	All	+0.226	.007	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ANKRD13C–HNSC

Open the HNSC breakdown →