ANKRD13C

Across TCGA patient cohorts, ANKRD13C mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD13C-associated genes across cancer lineages are ERK2, eEF2, and EGFR_pY1068. Each is linked with ANKRD13C in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD13C-to-partner and partner-to-ANKRD13C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by ANKRD13C-low versus ANKRD13C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD13C→partner) and Y-score (partner→ANKRD13C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.172	+1.765	.007	.013	3	2
UCEC	eEF2 →	+0.278	+2.000	.020	.029	3	1
UCEC	EGFR_pY1068 →	-0.299	-2.584	<.001	<.001	3	1
UCEC	eIF4E →	+0.221	+2.201	.001	<.001	3	1
UCEC	eIF4G →	+0.246	+1.321	.017	.029	3	1
UCEC	A-Raf_pS299 →	-0.151	-3.906	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

ERK2 by ANKRD13C expression — UCEC

Explore this box plot interactively →