ANKRD13C

Across TCGA cell cohorts, ANKRD13C mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANKRD13C-associated genes across cancer lineages are PRAMEF10, PRAMEF20, and PRAMEF17. Each is linked with ANKRD13C in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD13C-to-partner and partner-to-ANKRD13C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF10 grouped by ANKRD13C-low versus ANKRD13C-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD13C→partner) and Y-score (partner→ANKRD13C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PRAMEF10 →	+0.885	+4.643	<.001	.004	3	1
LUNG_SCLC	PRAMEF20 →	+0.362	+4.269	<.001	.005	3	1
LUNG_SCLC	PRAMEF17 →	+0.010	+4.643	<.001	.004	3	1
LUNG_NSCLC_LUAD	SMIM28 →	+0.038	+5.228	<.001	.005	3	1
LARGE_INTESTINE	TECRL →	+0.026	+4.977	<.001	.007	3	1
BLOOD_Leukemia	OR4F15 →	+0.006	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

PRAMEF10 by ANKRD13C expression — LUNG_SCLC

Explore this box plot interactively →