ANKRD13A

Across TCGA patient cohorts, ANKRD13A mutation is significantly associated with the RNA expression of many other genes, with 1,165 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD13A-associated genes across cancer lineages are CCDC116, LINC01943, and IGHV3-30. Each is linked with ANKRD13A in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD13A-to-partner and partner-to-ANKRD13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC116 grouped by ANKRD13A-low versus ANKRD13A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD13A→partner) and Y-score (partner→ANKRD13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC116 →	+0.225	+3.753	<.001	<.001	3	3
UCEC	LINC01943 →	+0.363	+2.627	.006	.005	3	2
UCEC	IGHV3-30 →	+2.016	+2.392	<.001	<.001	3	2
UCEC	CCL5 →	+0.998	+3.823	.001	<.001	3	2
UCEC	TAF9 →	+0.613	+2.828	<.001	.001	3	2
UCEC	IGHV2-70 →	+1.598	+4.095	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,165 associations by consensus.

CCDC116 by ANKRD13A expression — UCEC

Explore this box plot interactively →