ANKRD11

Across TCGA patient cohorts, ANKRD11 mutation is significantly associated with the RNA expression of many other genes, with 7,391 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD11-associated genes across cancer lineages are NDUFAB1, PIMREG, and COQ3. Each is linked with ANKRD11 in more than 4 cancer types. Because this analysis shows association rather than direction, both ANKRD11-to-partner and partner-to-ANKRD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFAB1 grouped by ANKRD11-low versus ANKRD11-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD11→partner) and Y-score (partner→ANKRD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NDUFAB1 →	+0.411	+2.842	.002	.001	3	5
UCEC	PIMREG →	+0.631	+1.406	<.001	<.001	3	5
COAD	COQ3 →	+0.357	+1.487	.002	.004	3	5
UCEC	GTSE1 →	+0.680	+1.801	<.001	<.001	3	5
UCEC	POLR1D →	+0.293	+2.374	<.001	<.001	3	5
UCEC	ECHS1 →	+0.280	+1.636	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,391 associations by consensus.

NDUFAB1 by ANKRD11 expression — HNSC

Explore this box plot interactively →