ANKRD11

Across TCGA cell cohorts, ANKRD11 mutation is significantly associated with the RNA expression of many other genes, with 1,640 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD11-associated genes across cancer lineages are SRR, ALDH3A1, and OTX1. Each is linked with ANKRD11 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD11-to-partner and partner-to-ANKRD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SRR grouped by ANKRD11-low versus ANKRD11-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD11→partner) and Y-score (partner→ANKRD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	SRR →	+0.873	+2.115	.005	.007	3	4
LARGE_INTESTINE	ALDH3A1 →	+1.820	+1.949	.002	.002	3	3
LARGE_INTESTINE	OTX1 →	+0.639	+2.584	<.001	.002	3	3
BLOOD_Leukemia	TCEANC2 →	+0.341	+2.437	.009	.007	3	3
LARGE_INTESTINE	INVS →	+0.484	+2.544	.004	<.001	3	3
LUNG_NSCLC_LUAD	COQ3 →	+0.600	+3.206	.004	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,640 associations by consensus.

SRR by ANKRD11 expression — OVARY

Explore this box plot interactively →