ANKRD10

Across TCGA cell cohorts, ANKRD10 mutation is significantly associated with the mutation status of many other genes, with 3,520 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD10-associated genes across cancer lineages are REV3L, SUPT6H, and MDGA1. Each is linked with ANKRD10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD10-to-partner and partner-to-ANKRD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REV3L grouped by ANKRD10-low versus ANKRD10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD10→partner) and Y-score (partner→ANKRD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	REV3L →	+2.340	+4.278	<.001	<.001	1	3
UPPER_AERODIGESTIVE_TRACT	SUPT6H →	+4.954	+4.392	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	MDGA1 →	+4.954	+4.392	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	RND3 →	+4.954	+4.392	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	ADCY4 →	+4.954	+4.392	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	ACLY →	+4.954	+4.392	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,520 associations by consensus.

REV3L by ANKRD10 expression — LARGE_INTESTINE

Explore this box plot interactively →