ANKRD10

Across TCGA pan-cancer cohorts, ANKRD10 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ANKRD10 data layer compared with 5 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ANKRD10 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ANKRD10 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

BLCA, ACC, and KIRC are the cancer types where ANKRD10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	II,III,IV	0.680	0.524	.001	81	view →
ACC	DFS	Median	All	0.276	0.620	<.001	80	view →
KIRC	DFS	Median	All	0.526	0.684	.003	57	view →
LGG	DFS	Median	All	0.661	0.813	<.001	44	view →
UVM	DFS	Quartile	All	0.294	0.863	<.001	39	view →
LIHC	DFS	Quartile	All	0.147	0.324	<.001	35	view →
SKCM	OS	Quartile	III,IV	0.793	0.525	.003	34	view →
GBM	DFS	Median	All	0.390	0.189	.003	20	view →
LUSC	DFS	Tertile	II,III,IV	0.264	0.526	.001	19	view →
DLBC	DFS	Median	All	0.604	0.929	.005	15	view →
SCLC	DFS	Tertile	II,III,IV	0.877	0.266	.006	15	view →
THCA	DFS	Quartile	II,III,IV	0.782	0.950	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ANKRD10–BLCA (OS)

Open the BLCA breakdown →