ANKRD1

Across TCGA cell cohorts, ANKRD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,234 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ANKRD1-associated GO terms across cancer lineages are Blood coagulation, extrinsic pathway, Endodermal cell differentiation, and Integrin-mediated signaling pathway. Each is linked with ANKRD1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ANKRD1-to-partner and partner-to-ANKRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood coagulation, extrinsic pathway grouped by ANKRD1-low versus ANKRD1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD1→partner) and Y-score (partner→ANKRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Blood coagulation, extrinsic pathway →	+1.158	+3.040	<.001	<.001	3	13
BONE	Endodermal cell differentiation →	+0.202	+3.350	<.001	.001	3	12
BONE	Integrin-mediated signaling pathway →	+0.214	+2.703	<.001	<.001	3	12
BONE	Negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II →	+1.776	+2.675	<.001	<.001	3	11
BONE	Negative regulation of epidermal growth factor-activated receptor activity →	+0.147	+4.217	<.001	<.001	3	11
BREAST	Blood coagulation, fibrin clot formation →	+0.451	+2.018	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,234 associations by consensus.

Blood coagulation, extrinsic pathway by ANKRD1 expression — LUNG_NSCLC_LUSC

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