ANKRD1

Across TCGA cell cohorts, ANKRD1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD1-associated genes across cancer lineages are KCNK17, ECE2, and INSL5. Each is linked with ANKRD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD1-to-partner and partner-to-ANKRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNK17 grouped by ANKRD1-low versus ANKRD1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD1→partner) and Y-score (partner→ANKRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KCNK17 →	+0.064	+2.906	<.001	.007	3	1
LARGE_INTESTINE	ECE2 →	+0.205	+2.791	.004	.005	3	1
LARGE_INTESTINE	INSL5 →	+0.231	+3.889	<.001	.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.012	+3.240	<.001	.004	3	1
LARGE_INTESTINE	FAM153B →	+0.512	+3.648	<.001	.002	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

KCNK17 by ANKRD1 expression — LARGE_INTESTINE

Explore this box plot interactively →