ANKMY1

Across TCGA cell cohorts, ANKMY1 mutation is significantly associated with the RNA expression of many other genes, with 502 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKMY1-associated genes across cancer lineages are LILRA5, SCGB1C1, and KRTAP5-4. Each is linked with ANKMY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKMY1-to-partner and partner-to-ANKMY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRA5 grouped by ANKMY1-low versus ANKMY1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKMY1→partner) and Y-score (partner→ANKMY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	LILRA5 →	+0.355	+4.930	<.001	.008	3	2
SOFT_TISSUE	SCGB1C1 →	+0.073	+5.977	<.001	.001	3	2
SOFT_TISSUE	KRTAP5-4 →	+0.028	+5.369	<.001	.004	3	2
LARGE_INTESTINE	PSMC1 →	+0.431	+3.252	.003	.002	3	2
LARGE_INTESTINE	GPR63 →	+0.770	+2.158	<.001	.004	3	2
LARGE_INTESTINE	RWDD3 →	+0.421	+3.459	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 502 associations by consensus.

LILRA5 by ANKMY1 expression — SOFT_TISSUE

Explore this box plot interactively →