ANKIB1

Across TCGA patient cohorts, ANKIB1 mutation is significantly associated with the RNA expression of many other genes, with 2,855 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKIB1-associated genes across cancer lineages are EIF3JP1, MED9, and EZH2P1. Each is linked with ANKIB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKIB1-to-partner and partner-to-ANKIB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF3JP1 grouped by ANKIB1-low versus ANKIB1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKIB1→partner) and Y-score (partner→ANKIB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	EIF3JP1 →	+0.117	+4.544	<.001	.009	3	3
UCEC	MED9 →	+0.224	+1.517	.007	.002	3	3
UCEC	EZH2P1 →	+0.181	+1.379	.007	.004	3	3
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	2
UCEC	RN7SL248P →	+0.043	+2.635	<.001	.003	3	2
BLCA	FECHP1 →	+0.028	+3.899	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,855 associations by consensus.

EIF3JP1 by ANKIB1 expression — LIHC

Explore this box plot interactively →