ANKHD1-EIF4EBP3

Across TCGA pan-cancer cohorts, ANKHD1-EIF4EBP3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ANKHD1-EIF4EBP3 data layer compared with 21 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ANKHD1-EIF4EBP3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ANKHD1-EIF4EBP3 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, HNSC, and LSCC are the cancer types where ANKHD1-EIF4EBP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.976	0.801	.014	10	view →
HNSC	DFS	Median	IV	0.496	0.893	.020	9	view →
LSCC	OS	Tertile	III,IV	0.887	0.444	.022	6	view →
CCRCC	DFS	Quartile	All	1.000	0.298	.036	2	view →
PDAC	OS	Quartile	III,IV	0.651	1.000	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ANKHD1-EIF4EBP3–UCEC (DFS)

Open the UCEC breakdown →