ANKH

Across TCGA patient cohorts, ANKH RNA expression is significantly associated with the protein abundance of many other proteins, with 14,528 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ANKH-associated proteins across cancer lineages are SULF1, THBS2, and CNN3. Each is linked with ANKH in more than 7 cancer types. Because this analysis shows association rather than direction, both ANKH-to-partner and partner-to-ANKH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKH versus SULF1 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKH→partner) and Y-score (partner→ANKH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SULF1 →	+0.804	+0.503	<.001	<.001	3	8
OV	THBS2 →	+1.608	+0.809	<.001	.007	3	8
OV	CNN3 →	+0.592	+0.686	.002	.008	3	7
UCEC	DAPK3 →	+0.601	+0.632	<.001	<.001	3	7
BRCA	FHL2 →	+0.673	+0.936	<.001	<.001	3	7
UCEC	MMP2 →	+0.819	+0.522	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,528 associations by consensus.

ANKH vs SULF1 — GBM

Explore this scatter interactively →