ANKDD1A

Across TCGA cell cohorts, ANKDD1A mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANKDD1A-associated genes across cancer lineages are RGR, CLRN1, and SIGLEC7. Each is linked with ANKDD1A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKDD1A-to-partner and partner-to-ANKDD1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RGR grouped by ANKDD1A-low versus ANKDD1A-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKDD1A→partner) and Y-score (partner→ANKDD1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	RGR →	+0.006	+5.087	<.001	.004	3	1
URINARY_TRACT	CLRN1 →	+0.033	+5.087	<.001	.004	3	1
OESOPHAGUS	SIGLEC7 →	+0.063	+4.906	<.001	.006	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	IQCF5 →	+0.121	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

RGR by ANKDD1A expression — URINARY_TRACT

Explore this box plot interactively →