ANK3-DT

Across TCGA pan-cancer cohorts, ANK3-DT RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ANK3-DT data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ANK3-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated ANK3-DT expression acts as an unfavorable survival marker, although some lineages such as BRCA and KIRC show a favorable association.

BRCA, KIRC, and OV are the cancer types where ANK3-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.662	0.480	<.001	93	view →
KIRC	DFS	Median	All	0.738	0.503	<.001	61	view →
OV	OS	Median	All	0.375	0.282	.012	48	view →
LGG	OS	Tertile	All	0.535	0.842	<.001	36	view →
BLCA	DFS	Quartile	III,IV	0.388	0.155	.004	33	view →
COAD	DFS	Tertile	All	0.678	0.436	<.001	33	view →
UCEC	DFS	Quartile	All	0.918	0.814	.006	30	view →
SARC	DFS	Tertile	All	0.606	0.467	.014	21	view →
SKCM	DFS	Tertile	III,IV	0.456	0.648	.023	20	view →
HNSC	OS	Median	All	0.820	0.711	.002	15	view →
ESCA	DFS	Tertile	II,III,IV	1.000	0.367	.026	12	view →
READ	OS	Median	III,IV	0.737	1.000	.009	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ANK3-DT–BRCA (OS)

Open the BRCA breakdown →