ANK2-AS1

Across TCGA pan-cancer cohorts, ANK2-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ANK2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ANK2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ANK2-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and PRAD show a favorable association.

KIRC, MESO, and CESC are the cancer types where ANK2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.642	0.825	.002	84	view →
MESO	OS	Tertile	II,III,IV	0.348	0.593	.010	45	view →
CESC	OS	Tertile	III,IV	0.230	0.686	.001	36	view →
TGCT	DFS	Tertile	II,III,IV	0.678	0.996	.012	24	view →
THCA	OS	Tertile	IV	0.579	1.000	<.001	24	view →
SKCM	OS	Tertile	III,IV	0.639	0.855	.011	21	view →
LUAD	OS	Tertile	IV	0.114	0.560	.038	18	view →
PAAD	OS	Tertile	All	0.863	0.299	.014	18	view →
DLBC	OS	Tertile	All	0.426	0.781	.014	18	view →
OV	OS	Tertile	IV	0.242	0.446	.009	12	view →
COAD	DFS	Tertile	All	0.587	0.799	.016	12	view →
PRAD	DFS	Tertile	All	1.000	0.743	.035	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ANK2-AS1–KIRC (DFS)

Open the KIRC breakdown →