Across TCGA patient cohorts, ANGPTL5 protein abundance is significantly associated with the RNA expression of many other genes, with 80 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ANGPTL5-associated genes across cancer lineages are RASL10A, ZBTB24, and LRRC31. Each is linked with ANGPTL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANGPTL5-to-partner and partner-to-ANGPTL5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPTL5→partner) and Y-score (partner→ANGPTL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RASL10A →	+0.961	+1.318	.004	<.001	3	1
BRCA	ZBTB24 →	+0.448	+1.493	.009	.001	3	1
BRCA	LRRC31 →	+2.588	+2.180	.001	.001	3	1
BRCA	TCEANC2 →	+0.550	+1.815	<.001	.003	3	1
BRCA	ANKRD13C →	+0.677	+1.879	.001	.009	3	1
BRCA	PMS2P5 →	-1.085	-1.515	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

Exploration

ANGPTL5 survival (RNA) · tumor vs normal (RNA) · all ANGPTL5 data types