ANGPTL2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANGPTL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,291 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANGPTL2-associated proteins across cancer lineages are TAGLN, TIMP2, and VCL. Each is linked with ANGPTL2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ANGPTL2-to-partner and partner-to-ANGPTL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANGPTL2 versus TAGLN in OV, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPTL2→partner) and Y-score (partner→ANGPTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTAGLN →+1.150+1.575<.001<.00139
BRCATIMP2 →+0.854+1.275<.001<.00139
UCECVCL →+0.555+0.612<.001<.00139
UCECMYL9 →+0.798+0.512<.001<.00139
BRCAPCOLCE →+0.820+1.360<.001<.00139
OVPDLIM7 →+0.757+1.833<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,291 associations by consensus.

ANGPTL2 vs TAGLN — OV

Per-sample scatter of ANGPTL2 vs TAGLN in OV (Pearson r = 0.74).

Explore this scatter interactively →

Exploration