ANGPT4

Across TCGA cell cohorts, ANGPT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,174 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ANGPT4-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of non-canonical NF-kappaB signal transduction, and Positive regulation of protein-containing complex assembly. Each is linked with ANGPT4 in more than 7 cancer types. Because this analysis shows association rather than direction, both ANGPT4-to-partner and partner-to-ANGPT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by ANGPT4-low versus ANGPT4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANGPT4→partner) and Y-score (partner→ANGPT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of myoblast fusion →	+0.111	+0.062	.002	.002	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of non-canonical NF-kappaB signal transduction →	+0.103	+0.100	<.001	.003	3	7
BLOOD_Lymphoma	Positive regulation of protein-containing complex assembly →	+0.030	+0.079	.002	.004	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of defense response to virus by host →	+0.099	+0.082	<.001	.001	3	6
OESOPHAGUS	Regulation of stress-activated MAPK cascade →	+0.102	+0.063	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.090	+0.076	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,174 associations by consensus.

Regulation of myoblast fusion by ANGPT4 expression — OESOPHAGUS

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