Across TCGA patient cohorts, ANG mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ANG-associated genes across cancer lineages are RPS28P1, COPS8P1, and MIR6877. Each is linked with ANG in more than 1 cancer types. Because this analysis shows association rather than direction, both ANG-to-partner and partner-to-ANG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANG→partner) and Y-score (partner→ANG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS28P1 →	+0.371	+5.027	<.001	.004	3	1
UCEC	COPS8P1 →	+0.286	+4.748	<.001	.003	3	1
UCEC	MIR6877 →	+1.280	+4.633	<.001	.004	3	1
SKCM	RN7SL870P →	+0.139	+5.097	<.001	.008	3	1
UCEC	RNA5SP426 →	+0.532	+5.453	<.001	.002	3	1
UCEC	RNA5SP419 →	+1.558	+4.661	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

ANG survival (RNA) · tumor vs normal (RNA) · all ANG data types