ANAPC4

Across TCGA cell cohorts, ANAPC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,987 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANAPC4-associated GO terms across cancer lineages are Positive regulation of organelle assembly, DNA-templated DNA replication, and Protein branched polyubiquitination. Each is linked with ANAPC4 in more than 16 cancer types. Because this analysis shows association rather than direction, both ANAPC4-to-partner and partner-to-ANAPC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by ANAPC4-low versus ANAPC4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC4→partner) and Y-score (partner→ANAPC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of organelle assembly →	+0.070	+0.811	<.001	<.001	3	17
SOFT_TISSUE	DNA-templated DNA replication →	+0.114	+0.866	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Protein branched polyubiquitination →	+0.112	+1.067	.002	.001	3	16
BLOOD_Leukemia	Replication fork processing →	+0.084	+0.635	<.001	<.001	3	16
BLOOD_Leukemia	DNA-templated DNA replication maintenance of fidelity →	+0.087	+0.629	<.001	<.001	3	16
BONE	Regulation of chromosome condensation →	+0.217	+0.742	.005	.003	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,987 associations by consensus.

Positive regulation of organelle assembly by ANAPC4 expression — URINARY_TRACT

Explore this box plot interactively →