ANAPC1P2

Across TCGA patient cohorts, ANAPC1P2 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ANAPC1P2-associated genes across cancer lineages are RN7SL654P, DEFB108D, and SPAM1. Each is linked with ANAPC1P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANAPC1P2-to-partner and partner-to-ANAPC1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL654P grouped by ANAPC1P2-low versus ANAPC1P2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANAPC1P2→partner) and Y-score (partner→ANAPC1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL654P →	+0.325	+4.694	<.001	<.001	3	2
UCEC	DEFB108D →	+0.286	+4.582	<.001	.005	3	2
SKCM	SPAM1 →	+0.025	+4.563	.001	.004	3	1
SKCM	SYT10 →	+0.012	+4.470	.005	.005	3	1
HNSC	RBMY1HP →	+0.024	+7.954	<.001	.008	3	1
LUAD	TRAPPC2P3 →	+0.094	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

RN7SL654P by ANAPC1P2 expression — UCEC

Explore this box plot interactively →