AMZ2P1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AMZ2P1 mutation is significantly associated with the RNA expression of many other genes, with 227 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMZ2P1-associated genes across cancer lineages are MIR4445, SNRPGP1, and RNU6-391P. Each is linked with AMZ2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMZ2P1-to-partner and partner-to-AMZ2P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMZ2P1→partner) and Y-score (partner→AMZ2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMIR4445 →+0.326+7.731<.001.00932
BLCASNRPGP1 →+0.270+5.106<.001.00832
UCECRNU6-391P →+0.281+3.442<.001.00432
UCECH3C8 →+0.795+3.245.004.00831
UCECRNA5SP414 →+0.723+2.769<.001.00231
UCECMIR7702 →+0.309+4.738<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 227 associations by consensus.

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