Across TCGA patient cohorts, AMZ2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,212 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AMZ2-associated proteins across cancer lineages are TACO1, DCAF7, and UBE2O. Each is linked with AMZ2 in more than 6 cancer types. Because this analysis shows association rather than direction, both AMZ2-to-partner and partner-to-AMZ2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AMZ2→partner) and Y-score (partner→AMZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TACO1 →	+0.406	+0.442	<.001	<.001	3	7
PDAC	DCAF7 →	+0.318	+0.307	<.001	<.001	3	6
OV	UBE2O →	+0.309	+0.619	<.001	<.001	3	6
HNSC	TXNDC5 →	-0.519	-0.522	<.001	.005	3	5
LSCC	HIC1_S248 →	-0.629	-0.572	<.001	<.001	3	5
LSCC	TRMT1L →	+0.383	+0.385	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,212 associations by consensus.

Exploration

AMZ2 survival (RNA) · tumor vs normal (RNA) · all AMZ2 data types