Across TCGA patient cohorts, AMZ2 mutation is significantly associated with the RNA expression of many other genes, with 1,627 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMZ2-associated genes across cancer lineages are MIR374A, TAAR5, and RNU6-492P. Each is linked with AMZ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AMZ2-to-partner and partner-to-AMZ2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMZ2→partner) and Y-score (partner→AMZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR374A →	+0.201	+2.577	.003	.006	3	2
UCEC	TAAR5 →	+0.140	+1.711	.005	.009	3	2
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	1
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	1
STAD	SNORD114-11 →	+0.493	+5.147	<.001	.001	3	1
STAD	UBE2Q2P5Y →	+0.156	+5.226	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,627 associations by consensus.

Exploration

AMZ2 survival (RNA) · tumor vs normal (RNA) · all AMZ2 data types