AMY2A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AMY2A protein abundance is significantly associated with the RNA expression of many other genes, with 941 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AMY2A-associated genes across cancer lineages are PPP1R16A, SLC25A1, and TRIOBP. Each is linked with AMY2A in more than 1 cancer types. Because this analysis shows association rather than direction, both AMY2A-to-partner and partner-to-AMY2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMY2A versus PPP1R16A in COAD, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMY2A→partner) and Y-score (partner→AMY2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPPP1R16A →-0.461-1.127.007.00332
PDACSLC25A1 →-0.294-1.075.003.00231
PDACTRIOBP →-0.292-0.802.002.00631
PDACDIDO1 →-0.217-0.833.001.00931
PDACPTK6 →-0.522-0.817.003.00131
PDACARFRP1 →-0.397-0.986.007.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 941 associations by consensus.

AMY2A vs PPP1R16A — COAD

Per-sample scatter of AMY2A vs PPP1R16A in COAD (Pearson r = -0.26).

Explore this scatter interactively →

Exploration