AMY2A

Across TCGA patient cohorts, AMY2A mutation is significantly associated with the RNA expression of many other genes, with 2,931 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMY2A-associated genes across cancer lineages are RNU6-701P, RNU6-906P, and LINC01853. Each is linked with AMY2A in more than 1 cancer types. Because this analysis shows association rather than direction, both AMY2A-to-partner and partner-to-AMY2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-701P grouped by AMY2A-low versus AMY2A-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMY2A→partner) and Y-score (partner→AMY2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-701P →	+0.214	+5.008	<.001	.004	3	2
LIHC	RNU6-906P →	+0.312	+5.305	<.001	.003	3	2
LIHC	LINC01853 →	+0.695	+4.758	<.001	.006	3	2
LIHC	SNRPCP10 →	+0.148	+4.544	.001	.009	3	2
HNSC	RPS27P1 →	+0.199	+4.736	<.001	.007	3	2
READ	RN7SKP39 →	+0.076	+5.096	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,931 associations by consensus.

RNU6-701P by AMY2A expression — LIHC

Explore this box plot interactively →