AMY2A

Across TCGA cell cohorts, AMY2A RNA expression is significantly associated with the go_rna of many other GO terms, with 224 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AMY2A-associated GO terms across cancer lineages are Polysaccharide digestion, Fatty-acyl-CoA metabolic process, and Membrane assembly. Each is linked with AMY2A in more than 5 cancer types. Because this analysis shows association rather than direction, both AMY2A-to-partner and partner-to-AMY2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Polysaccharide digestion grouped by AMY2A-low versus AMY2A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMY2A→partner) and Y-score (partner→AMY2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Polysaccharide digestion →	+0.137	+0.077	<.001	.002	3	6
PANCREAS	Fatty-acyl-CoA metabolic process →	-0.043	-0.018	.008	.009	3	3
LUNG_NSCLC_LUAD	Membrane assembly →	+0.044	+0.023	.004	.001	3	3
BLOOD_Leukemia	Immune response to tumor cell →	+0.109	+0.047	.003	.001	3	3
BLOOD_Leukemia	Cellular response to misfolded protein →	+0.053	+0.049	.001	.009	3	3
LUNG_NSCLC_LUAD	Regulation of toll-like receptor 7 signaling pathway →	-0.094	-0.043	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 224 associations by consensus.

Polysaccharide digestion by AMY2A expression — BREAST

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