AMY2A

Across TCGA cell cohorts, AMY2A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible AMY2A-associated genes across cancer lineages are MAGEB5. Each is linked with AMY2A in more than 1 cancer types. Because this analysis shows association rather than direction, both AMY2A-to-partner and partner-to-AMY2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB5 grouped by AMY2A-low versus AMY2A-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMY2A→partner) and Y-score (partner→AMY2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MAGEB5 by AMY2A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →