Across TCGA patient cohorts, AMY1C mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible AMY1C-associated genes across cancer lineages are MIR6893, LINC00208, and RNU1-49P. Each is linked with AMY1C in more than 1 cancer types. Because this analysis shows association rather than direction, both AMY1C-to-partner and partner-to-AMY1C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMY1C→partner) and Y-score (partner→AMY1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6893 →	+0.541	+5.037	<.001	.009	3	1
SKCM	LINC00208 →	+0.026	+6.624	<.001	.001	3	1
SKCM	RNU1-49P →	+0.298	+6.993	<.001	<.001	3	1
SKCM	MRPS16P1 →	+0.115	+5.292	<.001	.006	3	1
SKCM	NIFKP7 →	+0.060	+5.159	<.001	.007	3	1
SKCM	RNU6-579P →	+0.411	+5.097	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

AMY1C survival (RNA) · tumor vs normal (RNA) · all AMY1C data types