AMY1B

Across TCGA patient cohorts, AMY1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,061 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMY1B-associated GO terms across cancer lineages are Neutrophil activation involved in immune response, Antigen processing and presentation of exogenous peptide antigen, and Vitamin B6 metabolic process. Each is linked with AMY1B in more than 6 cancer types. Because this analysis shows association rather than direction, both AMY1B-to-partner and partner-to-AMY1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophil activation involved in immune response grouped by AMY1B-low versus AMY1B-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMY1B→partner) and Y-score (partner→AMY1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Neutrophil activation involved in immune response →	+0.029	+0.272	<.001	<.001	3	5
UVM	Antigen processing and presentation of exogenous peptide antigen →	+0.076	+0.013	<.001	.007	1	7
PAAD	Vitamin B6 metabolic process →	+0.033	+0.343	.003	.001	2	6
BLCA	Neutrophil degranulation →	+0.034	+0.026	<.001	.005	3	4
BLCA	Regulation of neutrophil degranulation →	+0.033	+0.013	.001	.005	3	4
PAAD	Cobalt ion transport →	+0.038	+0.570	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,061 associations by consensus.

Neutrophil activation involved in immune response by AMY1B expression — UCEC

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