AMY1A

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AMY1A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,683 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible AMY1A-associated GO terms across cancer lineages are Intracellular phosphate ion homeostasis, Aminophospholipid transport, and Polyadenylation-dependent RNA catabolic process. Each is linked with AMY1A in more than 2 cancer types. Because this analysis shows association rather than direction, both AMY1A-to-partner and partner-to-AMY1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular phosphate ion homeostasis grouped by AMY1A-low versus AMY1A-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMY1A→partner) and Y-score (partner→AMY1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCIntracellular phosphate ion homeostasis →+0.044+0.006.001<.00133
COADAminophospholipid transport →+0.045+0.003.003.00132
COADPolyadenylation-dependent RNA catabolic process →+0.035+0.003.005<.00132
ACCB-1 B cell differentiation →+0.059+0.005.001.00332
ACCMDA-5 signaling pathway →+0.066+0.007.002.00523
STADFolic acid metabolic process →+0.026+0.016<.001.00823
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,683 associations by consensus.

Intracellular phosphate ion homeostasis by AMY1A expression — LUSC

Box plot of Intracellular phosphate ion homeostasis in AMY1A-low vs AMY1A-high samples in LUSC.

Explore this box plot interactively →

Exploration