Across TCGA patient cohorts, AMTN mutation is significantly associated with the RNA expression of many other genes, with 1,290 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMTN-associated genes across cancer lineages are CDADC1, IMMP1L, and DCK. Each is linked with AMTN in more than 2 cancer types. Because this analysis shows association rather than direction, both AMTN-to-partner and partner-to-AMTN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMTN→partner) and Y-score (partner→AMTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDADC1 →	+0.430	+3.491	.006	.002	3	3
UCEC	IMMP1L →	+0.574	+3.491	.001	.002	2	3
UCEC	DCK →	+0.811	+3.470	.006	.003	3	2
UCEC	MAD2L1 →	+1.058	+3.191	.001	.009	3	2
UCEC	ABCE1 →	+0.811	+3.354	.002	.005	3	2
UCEC	NUDT2 →	+0.866	+3.459	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,290 associations by consensus.

Exploration

AMTN survival (RNA) · tumor vs normal (RNA) · all AMTN data types