AMOTL1

Across TCGA patient cohorts, AMOTL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,047 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible AMOTL1-associated proteins across cancer lineages are AMOTL1_S828, VCL, and PRKG1. Each is linked with AMOTL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both AMOTL1-to-partner and partner-to-AMOTL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMOTL1 versus AMOTL1_S828 in BRCA, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AMOTL1→partner) and Y-score (partner→AMOTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AMOTL1_S828 →	+0.938	+1.148	<.001	<.001	3	8
UCEC	VCL →	+0.494	+0.767	.002	<.001	3	7
OV	PRKG1 →	+0.669	+1.047	<.001	<.001	3	7
BRCA	AMOTL1_S906 →	+0.971	+1.551	<.001	<.001	3	7
OV	SERPINA4 →	+0.799	+1.013	<.001	<.001	3	7
CCRCC	SVIL →	+0.442	+0.543	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,047 associations by consensus.

AMOTL1 vs AMOTL1_S828 — BRCA

Explore this scatter interactively →