AMOT

Across TCGA patient cohorts, AMOT protein abundance is significantly associated with the RNA expression of many other genes, with 8,421 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMOT-associated genes across cancer lineages are NR3C2, BDH2, and S1PR1. Each is linked with AMOT in more than 4 cancer types. Because this analysis shows association rather than direction, both AMOT-to-partner and partner-to-AMOT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMOT versus NR3C2 in GBM, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMOT→partner) and Y-score (partner→AMOT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NR3C2 →	+1.038	+0.547	<.001	<.001	3	5
GBM	BDH2 →	+0.488	+0.430	<.001	<.001	3	4
GBM	S1PR1 →	+0.785	+0.458	<.001	<.001	3	4
GBM	LHFPL1 →	+1.060	+0.562	<.001	<.001	3	4
BRCA	BOC →	+0.920	+0.341	<.001	<.001	3	4
BRCA	CACHD1 →	+0.758	+0.323	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,421 associations by consensus.

AMOT vs NR3C2 — GBM

Explore this scatter interactively →