AMOT

Across TCGA cell cohorts, AMOT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,390 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AMOT-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Positive regulation of cell size. Each is linked with AMOT in more than 8 cancer types. Because this analysis shows association rather than direction, both AMOT-to-partner and partner-to-AMOT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by AMOT-low versus AMOT-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMOT→partner) and Y-score (partner→AMOT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of myoblast fusion →	+0.132	+2.176	<.001	<.001	3	9
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.128	+2.176	<.001	<.001	3	9
PANCREAS	Positive regulation of cell size →	-0.162	-1.413	<.001	<.001	3	8
OVARY	mRNA transport →	+0.072	+1.577	.002	.009	2	9
OESOPHAGUS	Blood coagulation, common pathway →	-1.309	-1.215	<.001	.003	3	8
BREAST	Regulation of G1/S transition of mitotic cell cycle →	+0.071	+1.777	.002	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,390 associations by consensus.

Negative regulation of myoblast fusion by AMOT expression — OVARY

Explore this box plot interactively →