AMN1

Across TCGA pan-cancer cohorts, AMN1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated AMN1 data layer compared with 19 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher AMN1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated AMN1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where AMN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.998	0.749	.003	27	view →
LUAD	OS	Tertile	III,IV	0.251	0.840	.007	21	view →
CCRCC	DFS	Median	II,III,IV	0.208	1.000	.019	14	view →
GBM	DFS	Tertile	All	0.857	0.674	.008	11	view →
HNSC	DFS	Median	II,III,IV	0.801	1.000	.014	8	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

AMN1–LSCC (OS)

Open the LSCC breakdown →