AMN1

Across TCGA pan-cancer cohorts, AMN1 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of AMN1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where AMN1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types AMN1 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

LSCC, CCRCC, and LUAD are the cancer types where AMN1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AMN1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	All	II,III,IV	+0.199	.010	6	view →
CCRCC	All	All	+0.172	.002	5	view →
LUAD	Female	II,III,IV	−0.388	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

AMN1–LSCC

Open the LSCC breakdown →