AMN1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AMN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,173 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AMN1-associated proteins across cancer lineages are PSMB8, UNC13D, and PSME1. Each is linked with AMN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both AMN1-to-partner and partner-to-AMN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AMN1 versus PSMB8 in LSCC, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AMN1→partner) and Y-score (partner→AMN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCPSMB8 →-0.333-0.556<.001<.00135
LSCCUNC13D →-0.484-0.543<.001<.00134
CCRCCPSME1 →-0.347-0.238<.001.00134
LSCCPSME2 →-0.452-0.703<.001<.00134
GBMSEC24A →-0.276-0.464<.001<.00134
LSCCSP110_S244 →-0.475-0.453.002.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,173 associations by consensus.

AMN1 vs PSMB8 — LSCC

Per-sample scatter of AMN1 vs PSMB8 in LSCC (Pearson r = -0.44).

Explore this scatter interactively →

Exploration