AMN

Across TCGA cell cohorts, AMN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,464 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AMN-associated GO terms across cancer lineages are Bundle of His cell-Purkinje myocyte adhesion involved in cell communication, Cytotoxic T cell degranulation, and Peptidyl-lysine oxidation. Each is linked with AMN in more than 8 cancer types. Because this analysis shows association rather than direction, both AMN-to-partner and partner-to-AMN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bundle of His cell-Purkinje myocyte adhesion involved in cell communication grouped by AMN-low versus AMN-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMN→partner) and Y-score (partner→AMN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Bundle of His cell-Purkinje myocyte adhesion involved in cell communication →	+0.803	+1.043	.005	.001	3	9
STOMACH	Cytotoxic T cell degranulation →	+0.302	+2.995	<.001	<.001	3	9
STOMACH	Peptidyl-lysine oxidation →	-1.331	-3.041	<.001	<.001	3	8
BREAST	Regulation of myoblast fusion →	+0.097	+0.992	<.001	.001	3	8
BONE	Negative regulation of RNA catabolic process →	+0.092	+1.758	<.001	.007	3	8
PANCREAS	Establishment or maintenance of epithelial cell apical/basal polarity →	+0.090	+1.059	.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,464 associations by consensus.

Bundle of His cell-Purkinje myocyte adhesion involved in cell communication by AMN expression — BLOOD_Lymphoma

Explore this box plot interactively →