AMMECR1L

Across TCGA patient cohorts, AMMECR1L mutation is significantly associated with the RNA expression of many other genes, with 5,715 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AMMECR1L-associated genes across cancer lineages are MTND1P29, EIF3JP1, and TDGP1. Each is linked with AMMECR1L in more than 1 cancer types. Because this analysis shows association rather than direction, both AMMECR1L-to-partner and partner-to-AMMECR1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND1P29 grouped by AMMECR1L-low versus AMMECR1L-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AMMECR1L→partner) and Y-score (partner→AMMECR1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MTND1P29 →	+0.100	+5.106	.009	.008	3	2
UCEC	EIF3JP1 →	+0.150	+1.903	<.001	<.001	3	2
UCEC	TDGP1 →	+0.130	+2.485	<.001	<.001	3	2
LUAD	RNA5SP175 →	+0.384	+4.722	.005	.003	3	2
LUAD	KRTAP10-10 →	+0.098	+4.554	<.001	.009	3	2
LUAD	RN7SL776P →	+0.097	+6.599	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,715 associations by consensus.

MTND1P29 by AMMECR1L expression — BLCA

Explore this box plot interactively →