AMIGO2

Across TCGA cell cohorts, AMIGO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,605 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AMIGO2-associated GO terms across cancer lineages are Coagulation, Integrin-mediated signaling pathway, and Blood coagulation. Each is linked with AMIGO2 in more than 12 cancer types. Because this analysis shows association rather than direction, both AMIGO2-to-partner and partner-to-AMIGO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Coagulation grouped by AMIGO2-low versus AMIGO2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMIGO2→partner) and Y-score (partner→AMIGO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Coagulation →	+0.140	+3.345	<.001	<.001	3	13
BONE	Integrin-mediated signaling pathway →	+0.231	+3.304	<.001	<.001	3	13
BONE	Blood coagulation →	+0.140	+3.345	<.001	<.001	3	13
CNS	Regulation of hemostasis →	+0.178	+2.367	<.001	<.001	3	12
CNS	Regulation of blood coagulation →	+0.180	+2.367	<.001	<.001	3	12
BREAST	Endodermal cell differentiation →	+0.190	+2.418	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,605 associations by consensus.

Coagulation by AMIGO2 expression — BONE

Explore this box plot interactively →