AMIGO1

Across TCGA cell cohorts, AMIGO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,086 significant associations in total. CNS shows the largest number of these associations.

The most reproducible AMIGO1-associated GO terms across cancer lineages are Cytoplasmic translation, Nucleic acid catabolic process, and Proton motive force-driven ATP synthesis. Each is linked with AMIGO1 in more than 13 cancer types. Because this analysis shows association rather than direction, both AMIGO1-to-partner and partner-to-AMIGO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by AMIGO1-low versus AMIGO1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AMIGO1→partner) and Y-score (partner→AMIGO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cytoplasmic translation →	+0.095	+1.105	.009	.006	2	14
UPPER_AERODIGESTIVE_TRACT	Nucleic acid catabolic process →	+0.054	+0.780	.005	.008	3	12
SKIN	Proton motive force-driven ATP synthesis →	+0.069	+0.764	<.001	<.001	3	12
OESOPHAGUS	Regulation of myoblast fusion →	+0.128	+1.112	.007	.006	2	13
SKIN	Negative regulation of myoblast fusion →	+0.106	+1.028	<.001	<.001	3	12
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.122	+1.211	.005	.002	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,086 associations by consensus.

Cytoplasmic translation by AMIGO1 expression — OESOPHAGUS

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