AMHR2

Across TCGA pan-cancer cohorts, AMHR2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated AMHR2 data layer compared with 10 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher AMHR2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated AMHR2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

HNSC, KIRP, and BRCA are the cancer types where AMHR2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.822	0.705	<.001	71	view →
KIRP	OS	Quartile	All	0.344	1.000	<.001	59	view →
BRCA	DFS	Tertile	IV	0.934	0.416	.004	38	view →
CESC	OS	Tertile	IV	0.747	0.282	.018	24	view →
UCS	DFS	Median	IV	0.367	0.952	.001	24	view →
UVM	DFS	Tertile	All	0.364	0.841	.003	18	view →
COAD	DFS	Tertile	IV	0.299	0.583	.025	16	view →
SCLC	DFS	Median	III,IV	0.968	0.338	.024	9	view →
TGCT	DFS	Median	All	0.572	0.779	.030	8	view →
KICH	DFS	Median	II,III,IV	0.657	1.000	.025	8	view →
DLBC	OS	Median	III,IV	0.272	1.000	.017	7	view →
ACC	OS	Median	IV	0.344	0.724	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

AMHR2–HNSC (OS)

Open the HNSC breakdown →